Supernatural: 20 Greatest Music Moments

20. "Highway To Hell" By AC/DC (1.1, "Pilot")

In the pilot episode of Supernatural, we are introduced to three very important characters: Sam, Dean, and Dean's car. With Sam and the Impala as the two arguably most important elements of Dean's life, he is conflicted when Sam saves the day--and his own life--by driving the car into a house. Once he is certain that Sam is alive and more or less intact, Dean immediately begins to worry about his "Baby," threatening to kill his beloved younger brother if she was damaged. In the next scene, we see the Impala roaring off into the night, one headlight out with "Highway To Hell" blasting out of the speakers.

19. "Don't Fear The Reaper" By Blue Oyster Cult (1.12, "Faith")

In "Faith," we see one of the earliest instances in which one of the Winchesters is dying. (Spoiler: it happens a lot.) When Sam drags a dying Dean to a faith healer, the boys discover--after Dean is restored to health--that the healer is harnessing the power of a Reaper to exchange one life for another. Then, to the tunes of Blue Oyster Cult's most famous song, we see a Reaper pursuing a terrified young jogger through the woods. The forest chase is intercut with a scene of the healer placing his hands on an infirm elderly man. Just as the song swells into the chorus, the jogger dies, and the elderly man rises from his wheelchair, the Reaper having appeared behind him and laid its hand on his head.