If 2018's Spider-Man: Into the Spider-Verse taught folks anything, it's that Spider-Man isn't the only Spider-Person in the Marvel Multiverse.
That's something comic book fans have known for some time, and while there are tons of alternate Earths showcasing different versions of Marvel's characters, ole Web-Head seems to be more involved than most.
And of course, where there's a Spider-Man, there's a disturbingly large rogues' gallery of his greatest villains, and like the Friendly Neighbourhood Spider-Man they all hate with a passion, each villain is different, depending on where they happen to come from in the Multiverse.
Sometimes, they are gender-swapped, as Doc Ock was in the film, but other times, they are something else altogether.
The great thing about Marvel's Multiverse is the ability for artists and writers to test their creativity, and one of the most interesting ways to do this is by making changes to a hero's villains, and Spidey has plenty to spare.
There are far more alternate versions of Spider-Man's villains than there are different versions of Spidey himself, which makes pinning down the best ones a rather difficult task.
There are plenty more to choose from, but these alternate versions of Spider-Man's foes are arguably some of the best his rogues' gallery has to offer.
10. Green Goblin Of Earth-1610
Over in the Ultimate Universe, otherwise known as Earth-1610, Norman Osborn became the Green Goblin, but not in the same way as in Earth-616.
Osborn was working on the Super-Soldier drug for S.H.I.E.L.D., and after seeing an Oz-injected spider bite result in turning Peter Parker into Spider-Man, he got an idea.
He theorized that infusing the Oz Formula with his own DNA would transform him into a better version of himself, and he was somewhat right and horribly wrong at the same time. The experiment didn't go according to plan, and an explosion resulted in turning him into a giant monster.
He learned how to control the transformations through OZ injections, but it wasn't long before he went the full supervillain. He targeted Spider-Man, and even tried to get the wall-crawler to kill Nick Fury. Of course, Spidey refused, which didn't sit well with the Goblin, furthering their antagonistic relationship a bit.
In terms of appearance, he's a giant green goblin, as his name implies. He has large horns, bleeds orange, sees everything in a red filter, and stands at seven feet tall, weighing in at about 1,000 lbs.
He can create fiery bolts of energy, is superhuman in terms of strength, speed, dexterity, healing, stamina, agility, and reflexes, and thanks to the Oz formula, he's immortal.