10 Most Evil Spider-Man Villains

4. Vermin

Vermin Marvel
Marvel Comics

Vermin is something of a forgotten Spider-Man villain, despite featuring in one of the wall-crawler's most acclaimed tales: Kraven's Last Hunt, by J. M. DeMatteis and Mike Zeck.

The character is essentially just a mutated humanoid rat. Only, instead of raising a band of kickass ninja turtles to help save New York, he just abducts victims off the street and devours their flesh.

But of course, Vermin wasn't always Vermin. To begin with, he was a scientist who worked for Baron Zemo, until one day he became the victim of their experiments. His mind and body were completely ruined by the incident, rendering him incapable of fighting his animalistic urges.

Ultimately, Vermin is a bit of a tragic character. His time at Ravencroft after suffering defeat at the hands of Spidey and Captain America did him a world of good, but his humanoid-rat form just kept on finding a way back, which inevitably led to more terrifying fates for unsuspecting New Yorkers.

Content Producer/Presenter

WhatCulture's very own resident movie guy, Ewan has been working in the content creation biz for over 10 years now, having started as a freelance contributor to WhatCulture Gaming all the way back in 2015. After graduating with a First-Class Honours in History from Northumbria University in 2017 (where he won a prize for a totally killer dissertation on the Watergate years), Ewan took on the role of Comics Editor at WhatCulture and quickly developed WhatCulture Comics into one of the biggest superhero-focused channels on YouTube. He followed this with a brief hiatus at Screen Rant in 2021, where he worked across the Gaming and Film sections as a writer and editor, before returning to WhatCulture as a Senior Content Producer / Presenter in 2023. He started his own podcast, We Love Dad Movies, in 2022, and has contributed several written pieces to the Eisner-nominated comics website Shelfdust as well. In his current role, Ewan incorporates his love of cinema, comic books, and history into written pieces and video essays for WhatCulture's Film & TV channel, as well as WhatCulture Gaming and WhatCulture Horror, with a particular focus on nineties-era Dad Movies, old school Westerns, and Golden Age Hollywood Noir. John Carpenter is his fave, and he thinks Batman Beyond should never have been cancelled. If that's your vibe, you'll probably like his stuff.