An act which was repayed unwittingly during the final Doctor Octopus story. Dying of a degenerative disease himself, his final act before dying sees the supervillain coaxing Spider-Man into visiting, during which time he swaps their brains. Peter Parker's mind goes into Ock's body, dies, and then Otto Octavius inhabits the body of Spider-Man! Dan Slott's Superior Spider-Man story caused no shortage of controversy and outrage when it happened, no doubt aided by the writer insisting that Peter Parker was gone for good, and Spider-Man with Doctor Octopus's brain was the status quo going forward. Which it obviously wasn't. Before things went back to the normal, though, Slott really messed with readers by dedicating a whole issue of Spider-Ock realising there were remnants of Peter Parker's mind still floating around and chastising him, so he put on a special helmet so he could hunt down those lingering memories and delete them. Permanently. For a bit.
Tom Baker is the Comics Editor at WhatCulture! He's heard all the Doctor Who jokes, but not many about Randall and Hopkirk. He also blogs at http://communibearsilostate.wordpress.com/