What Happened To Everyone Who Held The Infinity Gauntlet?
6. Mr. Fantastic
An exception for those who have wielded the Gauntlet, Mr. Fantastic did so only so that he could attempt to will the Infinity Gems themselves out of existence, after having tracked each stone down with the assistance of the Illuminati, comprised of himself, Doctor Strange, Professor X, Namor, Black Bolt, Iron Man, and Captain America.
Unfortunately for Reed Richards, his plan doesn't work. The gems themselves cannot be destroyed by the Gauntlet, and so he resolves to never again use the weapon, and instead divvies up the rest of the stones to his cohorts.
Shenanigans ensue, and the Illuminati find themselves at the centre of Thanos and the Black Order's conquest of the galaxy in 2013's Infinity. Needless to say, engaging in a grand conspiracy to keep the gems on Earth when there were far more qualified cosmic entities available to do so didn't exactly end well, so you can tick Richards' tenure with the Gauntlet as being something of an unfortunate one.