1. Ryan Reynolds
Twitter Handle: @VancityReynolds Without any shadow of a doubt, the most entertaining comic book actor on Twitter is Ryan Reynolds. The Deadpool star (who has also previously played another version of Wade Wilson, Green Lantern Hal Jordan and Hannibal King) proves in no uncertain terms that he is perfect for the role of the Merc with a Mouth - by actually being the Merc with a Mouth. https://twitter.com/VancityReynolds/status/647769278863810560 In addition to being generally hilarious, Reynolds often posts Deadpool-related tweets, including behind-the-scenes shots and videos of himself in make-up/costume. Plus, he promotes a number of great charities and, when he does reply directed to tweets from fans, it's usually funny as hell. When Deadpool is closer to being released - and once it is actually released - he's guaranteed to be tweeting all kinds of funny stuff.