Avengers 4: 15 Big Questions From Everything We Know So Far
4. Is Red Skull Done?
What We Know
When Gamora and Thanos traveled to Vormir to find the Soul Stone, they encountered a cursed Red Skull, who had been press-ganged into being the Stone's Guardian for his obsessive desire to collect the Infinity Stones (or at least one of them).
When Thanos retrieved the Stone by sacrificing Gamora, he was seemingly transported away from the mountain top and given the Stone and nothing more was heard of the Guardian.
What We Need To Know
Was that it for Red Skull? If the Soul World is to be introduced, he will likely be a valuable secret keeper who will need to be consulted by whoever goes after Gamora, which means he could return.
But if he has no Stone to guard, how can he be a Guardian?
The other thing that suggests he might not be done is the fact that he's cursed. It's not like the Stone being in possession of someone necessarily means he'd just be freed of that curse. It seemed more like your eternal sort of deal, after all. So he could still be stuck haunting Vormir.