Avengers: Infinity War - 15 New Details Marvel Just Revealed
13. The Hulkbuster Returns

Anyone hyped by the mention of the Hulkbuster being around in the MCU still in Spider-Man: Homecoming (where it's transported to the Avengers Facility in upstate New York) will be delighted to hear that the suit returns in Infinity War. It was shown very briefly in the footage on show at D23.
Does that mean the Hulk himself actually needs busting? Or is it being used only because it's useful for fighting large, strong enemies? If it's the former, that's a wonderful turn of events, and it wouldn't be entirely unprecedented since the Mind Stone could control him in either of the ways already seen (either through total hypnosis or through the manipulated influence Scarlet Witch used on him in Age Of Ultron).
That's probably too much like repetition though, so maybe just expect it to be employed against the Black Order.