Speaking of which, you should absolutely open up your inventory and give a good once-over to any unfamiliar items you pick up. They might be more important than you think. Obviously, though, if you're gonna do that make sure you're in a safe area any number of newbie deaths could be avoided if players realised that the options menu doesn't actually pause the game, and leaves you susceptible to attack. But you never know when an odd little item might come in handy. Without spoiling anything, there's an item you get by knocking at somebody's window also, sub-tip: knock on every door and window you come across that has a red lantern burning outside; mostly it's world-building stuff, but sometimes you get cool swag that winds up being vital in a certain boss battle. That's the sort of thing you wouldn't be aware of if you didn't read the item description. In the same way that rare items of great power might go unused in your inventory if you just pick them up in the wild without explanation. Especially if you're looking for stuff to offload in the Hunter's Dream (the safe area of the game), look at the description first to make sure you're not losing anything important.
Tom Baker is the Comics Editor at WhatCulture! He's heard all the Doctor Who jokes, but not many about Randall and Hopkirk. He also blogs at http://communibearsilostate.wordpress.com/