5. Galaxy-class
Key Appearances: Star Trek: The Next Generation, Star Trek: Generations, The Jem'Hadar, What You Leave Behind The Galaxy-class was the mainstay of Starfleet during the Next Generation era and U.S.S Enterprise-D was the flagship of the fleet after its commissioning. The Galaxy-class was the most powerful ship in Starfleet and one of the best in the quadrant as a whole, participating in safeguarding the borders of the Federation as well as participating in deep-space exploration. The Galaxy-class featured prominently in propelling Borg attacks, keeping the peace between the major factions in the quadrant as well as helping defend the Federation from the Dominion. The Galaxy-class isn't quite as aesthetically pleasing as some of the other designs used in the U.S.S Enterprise series, as it was always a little bit too compressed compared to some of the more streamlined vessels in Starfleet. Nevertheless, a Galaxy-class starship was the featured vessel in the best Star Trek series so it had to feature highly on this list.