10 Biggest Catastrophes In DC Comics
3. Final Crisis
Although decidedly not the final crisis that the DC universe would face, Final Crisis is the end of the 'main' DC crisis events - being predated by Crisis on Infinite Earths, Zero Hour: Time of Crisis and Infinite Crisis.
With the event marking the beginning of Darkseid gaining the Anti-Life Equation - which, as the name suggests, is a very bad thing - it sees our heroes race against the villain as he slowly tries to take over both their world and their universe.
While the event had some less catastrophic moments, like discovering that Barry Allen was still alive, having managed to literally outrun death, it still involved unimaginable levels of destruction, and saw what technically was the brief end of the DC universe entirely, before it was fixed by the convenient plot device that is the Miracle Machine.
Had this not worked however, we would have been left with a universe where Batman, Martian Manhunter and New God Orion were all dead - and those alive had been enslaved to serve a life of suffering under Darkseid.