4. Titano (DC Comics)
Titano is a Kryptonite-empowered chimpanzee who grew to epic proportions thanks to an incident that occurred in space and who is otherwise an absolutely blatant rip-off of King Kong (climbing tall buildings and all that jazz). He was once a relatively normal, but extremely intelligent chimpanzee called Toto. Lois Lane befriended Toto at a charity get-together when she cleaned some pie from his face, which had been accidentally thrown at him by a slapstick comic who was performing nearby. Toto was then selected to participate in an experimental week-long space rocket mission. Whilst in space on said mission, a Kryptonite meteor collided with a passing Uranium meteor and the radiation from the combined elements drifted across Toto's space pod, altering Toto's genetic structure as a result. When Toto's pod returned to Earth, he initially seemed to be completely unaffected by the incident. However, moments after exiting the pod, his size and strength suddenly grew to gigantic proportions. Lois Lane was present at the time, reporting on Toto's return, and he recognised her. In a moment stolen straight from King Kong (as previously referred to), he picked her up and climbed the Daily Planet building, prompting Superman in to action. Of course, it was at this point that we first saw the reason he's in this list - his Kryptonite eye-beams. They proved very problematic to the Man of Steel, but Lois tricked Titano in to putting on a pair of lead-lined, giant glasses (yes, really) which blocked his eye-beams and allowed Superman to get to her.