10 Villains Spider-Man Has NEVER Defeated
6. Baron Mordo
Having been co-created by the same guy - Steve Ditko - Spider-Man and Doctor Strange have crossed over multiple times throughout their lives.
Of course, these team-ups consist mainly of taking on their respective villains together. However, considering the kind of threats that Doctor Strange takes on on a regular basis, it stands to reason that Spidey is more often than not little more than moral support.
Hence why Baron Mordo, arch enemy of Stephen Strange, is on a list like this. Spider-Man, while having been present for his defeats, was rarely if ever the direct cause of said defeats.
The most notable time these two have faced off is, oddly, the Spider-Man animated series from the nineties. And even then, Spidey couldn't really defeat him on his own (didn't help that he had help from Carnage at the time). Spidey had to enlist the aid of Doctor Strange, Iron Man, and Venom of all people to help take him down.
The heroes just barely manage to send Carnage and Mordo's master Dormammu into the Dark Dimension, while Mordo escapes to be fought another day.