15 Greatest Marvel Comic Book Villains Of All Time

10. Venom

While being transferred to hosts like Mac Gargan and Flash Thompson has watered down the Venom symbiote somewhat in recent years, this alien bonding with Eddie Brock to create a twisted version of Spider-Man made for some truly terrifying tales in the 1980s. Unable to detect his presence via spider-sense, Peter Parker was at his most vulnerable against this vengeful reporter/shunned alien suit, and Venom has very nearly killed him a number of times.

However, one of Venom's most shocking moments came when he invaded the hero's home, threatening Mary Jane and leaving her utterly terrified of the monster she had just seen. As a "Lethal Protector" a few years later, Eddie may have flirted with the idea of being a hero of sorts, but he always returned to his villainous ways because his hatred for Spider-Man was far too great to ever let him leave the wall-crawler alone!