Avengers: Infinity War - Every Character Ranked By How Likely They Are To Die
19. Drax

He might have been moulded into a more comedic character in Guardians Of The Galaxy Vol 2, but Dave Bautista's Drax is still defined by one thing above all else - his burning rage at the murder of his wife and daughter by Ronan. And since he vowed to take vengeance on Thanos as well as Ronan, you have to think that he'll lose any sense of restraint when he comes face to face with the Mad Titan in Infinity War.
And while Drax has killed Thanos in the comics and is an extremely powerful character even in the MCU, there's no way that will end well for him. He might be protected by James Gunn's reluctance to leave him out of Guardians Vol 3, but we can certainly expect him to go berserk and end up heavily injured on Titan.
18. Nick Fury

Though he's been off the map since Avengers: Age Of Ultron (when he was found loitering around Clint Barton's farm), Samuel L Jackson will be back in the MCU before too long. And he might have said he won't appear until Captain Marvel, but the very idea of the Avengers struggling to come back together and Fury not being a driving force in their eventual resolution is unthinkable. That's essentially all he's good for now.
On top of all that, Fury said he was going to lead the charge against HYDRA from underground when he left in Captain America: The Winter Soldier, and we know that Steve Rogers, Falcon and Black Widow will be doing the same when we meet them first in Infinity War. So it would make sense that they're acting on Fury's orders.
The fact that he's so needed by the Avengers could also spell disaster for him - especially as he rather cynically profited from Loki's murder of Phil Coulson to get the team together in the first place. There'd be some karmic poetry to him dying in a similar way here.