10 Invincible Video Game Enemies That Pissed Everyone Off

4. Nemesis - Resident Evil 3 Remake

You can sub in your favourite Resi entry and giant invincible stalker-type here because Nemesis and Mr. X both apply to this list just fine. We’ve gone with Nemesis in Resident Evil 3 Remake because even though you can stun the Tyrant by dealing a significant amount of damage to him, you’re not going to be able to stop him completely.

That said, this is Resident Evil so you really should hold on to your ammo wherever possible, so you’re probably better off turning tail when the big guy clocks you.

Occasionally he’ll drop Umbrella Supply Boxes when you down him so you can grenade the heck out of him to try and nab those, but otherwise just stay out of his way until the end of the game when you’re finally able to defeat it once it’s mutated into its second form.

Of course, whether it’s actually dead at this point or if it’s just mutating again is anybody’s guess but let’s just assume you got it.