10 Most Terrifying Enemies In Resident Evil History

Added specifically for the RE1 remake, Lisa's story is a tragic one, so not only does she scare the hell out of you with her... well, everything, but her story is also a depressing one. It's a really lovely one-two punch all round.

Kidnapped at a young age by Ozwell Spencer and used as a test subject for the Progenitor virus and as her body mutated over time, her physical and mental state were disgustingly reconstructed. Lisa was continued to getting tested on for years and years, unfortunately surviving each one, then they decided to inject her with a Nemesis parasite, again, she survived and adapted its powers.

With all the experimentation she has become immune to so many types of damage, making her arrival a "F*ck that!" situation.

What's the icing on the cake is the encounters with her, no foreshadowing, no music or ambience, just the subtle rattle of chains, and when she's close enough, cries for help... and her mother.