10 Times Main Characters Killed Each Other
7. Clementine Killed Lee - Telltale's The Walking Dead
Telltale's The Walking Dead offers up one of the most heartbreaking instances of this, because there's absolutely no malice at all in one main character's decision to kill another.
Players spend the vast majority of the episodic adventure's first season controlling survivor Lee, but near the end of the penultimate episode, he's bitten by a walker, dooming him.
And so, the season finale ends with a shift of perspective to Lee's surrogate daughter Clementine, as players must choose whether to shoot Lee before he turns into a walker, or leave him to become one.
While players don't need to kill Lee, then - and, you can argue, he's basically already dead anyway - the post-episode player choice survey makes it clear that the overwhelming majority of people decided to put Lee out of his misery rather than let him shamble around as one of the undead.
From this point on, regardless of which ending you choose, the rest of the mainline series follows the adventures of Clementine as its true protagonist.