22. Wilson Fisk
Fisk is the notorious crime lord who runs the majority of gang related crime operations in New York, but for this Spider-Man outing, he acts only as the game's tutorial.
It's a shame that there couldn't have been some more interaction with Kingpin besides defeating his goons at certain locations or random crime interactions, but after defeating him in the game's opening mission, his presence is only ever felt through henchmen.
The importance of Fisk's role in the underworld of the Big Apple is never understated, with his incarceration serving as the springboard for Martin Li's plan. Without Kingpin there to run things, everyone else can step up in to his undoubtedly massive shoes.
But aside from sparking the main story alight with his capture, he doesn't offer anything else to the overall experience.