10 Worst Things That Ever Happened To Deadpool

The first worst thing to ever happen to the mercenary with a mouth is the very thing that turned him into the renegade he is today - his cancer. Without his cancer, nothing else that has happened in the 29 years since would have ever come to pass.

His insanity, his continual loss of family and friends and any loved ones, any chance for having a normal life, being trapped in a constantly rotting body, his torment with not being able to die and end his suffering, all of it came from something that affects thousands of people in the real world, something we still can't cure, nor is cured in the fantastical world of Marvel.

Every other immortal in the Marvel universe lives in a body that they can control, which works with them in relative harmony. But Wade Wilson has been fighting with his body ever since he became a mutant, his mind constantly shattering into a thousand pieces due to the unimaginable pain.

Wade Wilson lives every single second of his sometimes disfigured life being constantly torn apart by his cancer as it kills every cell in his body, only for those cells to be sown right back together by his imperfect healing factor, including his immortal cancer cells that can never be removed or cured.