8. Professor Pyg
DC Comics
First Appearance: Batman No.666, 2007
Traits: Skilled Surgeon, Chemist, Insane Professor Pig might be a relatively late addition to the roster but he's one of the most horrifying adversaries that Batman has ever faced. With an insane cruelty rivalling even the Joker, many of his storylines have been among the darkest and scariest of any in Batman's long history. A genius surgeon, Professor Pyg is obsessed with making people 'perfect'. He does this by turning his victims into 'Dollotrons', permanently fusing a doll's face onto them and lobotomising them so that they'll do his bidding. Much of the praise given to the Arkham series was down to its darker elements, so we'd be all for a full on horror-themed Batman game. With a new horror direction, a relatively unknown villain would be far more effective, and we think Professor Pyg would be perfect for the part.