7. An All Inclusive Setting
Star Trek is incredibly vast in its scope, so the developers would have to pick an era and run with it. The Next Generation seems like a good choice, mostly because there are a considerably high number of races in the story by this point, but there are still stretches of space that are largely unexplored. Voyager takes place after TNG and really plays up the unexplored space angle, but there is a problem there, the game would need The Space Federation to have a considerable presence in order to provide certain expected game mechanics, like upgrades and purchases. It would be a bit lame to feature a game where the player was essentially alone in a vast sector but somehow managed to buy parts for their ship etc. There is also the design aspect of TNG that players would find appealing, along with the Holo-Deck which could have nearly limitless possibilities (can you say, A Death Match mini game that completely fits into the game itself?) Considering that TNG is the most widely recognized of the various TV shows it seems like the setting that is most central to all fans.