There are many circumstantial factors that may impede an individual from reaching their truest potential, but they don't have to let them, if they so choose. With enough discipline, perseverance and a never-give-up attitude, a person will not only be able to achieve their intended goals, but vanquish the obstacles in their way.
You only need look to various success stories in life, such as American businessman Chris Gardner, or iconic film characters such as Rocky Balboa. The opposition in their life's journey was not enough to prevent them from finding success in their respective paths.
Whether these characters were part of our shared history, or fictional in their various properties, they refused to give in to the odds that were stacked against them. Gaming has had its own fair share of underdogs as well, who were met with very bleak circumstances, but managed to rise above them by the end of their journey.
Each character's journey may have differed vastly from one another's, but they all found it within themselves to rise above their initial obstacles, and change the trajectory of their respective footpath.
When there is a will, there is a way, as the old adage goes. As for these video game characters, they made sure to dig deep within themselves in order to find that way...