Resident Evil: Ranking Every Boss From Worst To Best

Appears In: Resident Evil 4

Osmund Saddler seemingly popped up out of nowhere in the early 2000s. This former bio-weapons expert now turned Spanish Emperor Palpatine discovered the mind control properties of Los Plagas and quickly took advantage of this for himself.

Creating the Los Iluminados cult, his influence spread throughout rural Spain, even manipulating young Ramon Salazar to do whatever he commanded. Once he had Salazar, the battle for power was over and he soon turned his gaze to that of world domination.

This is where Ashley Graham came in, as if he could control the president's daughter - like he had done with Salazar - then eventually he would have influence over the entire American government. Achieving this with the help from Jack Krauser - in return for a dominant Plagas parasite - Saddler soon had everything he needed to execute his plan, but didn't account for the president sending Leon S. Kennedy to retrieve her.

How To Beat:

At first glance, it might seem as if Saddler will go down pretty easy, but all it takes is for a single cutscene for a character in Resident Evil to mutate into something horrible.

Much like William Birkin from RE2, the bigger they get, the more eyes grow, and these eyes across Saddler's body will serve as handy weak spots - such as a giant one which has now grown out of his mouth.

At the same time, there will be handy cranes with tons of metal beams to swing into the beast in case Leon needs that little edge. Saddler can defect them back at Leon, so it's a gamble.

Ending the only way a final boss fight with Leon can go, Ada just seems to have a rocket launcher to hand which should be used for the killing blow - what would Leon ever do without Ada Wong?