10. Thanos (Marvel Comics)
Thanos is a mutant. Though not from Earth like, for example, the mutants who are in the X-Men, he is the planet of Titan's equivalent. A genius, Thanos is capable of inventing and plotting schemes that would cause powerful foes immense trouble even if he wasn't incredible powerful by default - which of course he is - as his schemes generally display ambition to acquire items that allow him to rule the universe, such as the Cosmic Cube, the Infinity Gauntlet and the Heart of the Universe. But it's his baseline powers that we're concentrating on here... Physically, Thanos is a beast, possessing superhuman strength which dwarves that of the likes of Hulk and Thor and durability that allows him to completely shrug off an all out physical attack from the Silver Surfer. He is also very quick - not necessarily in terms of his travel speed, but in terms of his reflexes. For example, when a faster-than-light Silver Surfer attacked him, he was able to react to the attack and defeat the Silver Surfer. He also boasts a whole host of esoteric powers and abilities (which earn him his place on this list) such as telepathy of a level that allows him to hold off mind attacks from the likes of Moondragon, teleportation, powerful energy blasts, the ability to manipulate various types of energy and matter transmutation (which enables him to reshape matter, as well as being able to reform himself if he is transmuted by an opponent). As a side note, this makes his imminent inclusion as a main villain in the Marvel cinematic universe extremely exciting.