10 More Evil Video Game Villains You Couldn't Wait To Kill

7. Mr X - Resident Evil 2

Resident Evil 2
Capcom

A lot of people, myself included, completely forgot that Mr. X was even in Resident Evil 2. After the recent remake though, it's guaranteed that nobody will be forgetting this big guy anytime soon. The franchise isn't a stranger to persistent enemies that can't be killed until a specific boss fight, but X might be the most intimidating one yet. Yep, even more so than Nemesis.

Every time the fashion-savvy bioweapon pops up - either in a horrifying silhouette down the corridor from you, or poking his head around the corner like the cheeky, hulking scamp that he is - you know you'll have to drop everything if you want to make it to your next objective without being punched into another dimension. Even if he doesn't kill you that much, his mere appearance is enough to get your heart racing, as is his thumping footsteps that let you know he's nearby.

Eventually, after hours of torment, you get the chance to go toe-to-toe with the big bad, inflicting plenty of pain with pistols, shotguns, magnums, flamethrowers and grenade launchers. Of course, he shrugs most of these off as mere flesh wounds, and it takes a rocket point-blank to the chest to take him out.

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Josh has over 11 years of experience as a published writer, having worked nine of those years as a full-time content producer at WhatCulture. In that period he has created hundreds of articles, videos and podcast episodes for multiple WhatCulture channels, specialising in gaming, horror and film & TV. He now primarily works as a senior content producer and presenter on WhatCulture Gaming where he co-hosts the WhatCulture Gaming Podcast, a top 3 UK most listened to gaming podcast that he co-created in 2018. Over the years he has reviewed several high-profile gaming releases, covered industry events with on-site reporting, opined on breaking news, and even kicked off his interviewing career by chatting to childhood hero, Tommy Wiseau.