9. The End (Metal Gear Solid 3: Snake Eater)
Metal Gear Solid 3's The End is by no means a difficult boss to overcome considering that he can be sniped earlier on in the game, negating the need to fight him directly - just be sure to dodge out of the way of his flying wheelchair!
But if you want to get even lazier, there's an easier method that will send him off to meet his maker without you having to do anything remotely taxing: all you'll need to do is manipulate a simple setting.
Once you reach The End's proper boss battle during the game, save, quit, and set your system's clock ahead by seven or eight days. Once you load up your save again, you'll be greeted by a special cutscene that shows Snake approaching The End, knife in hand, ready to strike... only to discover that his opponent has died of old age.
It's hilarious to watch the normally badass boss keel over and show his leathery, wrinkly face, but it's also quite sad to imagine him just hanging out in the boss arena for all those years, waiting for Snake to show up.