4. Skyrim
"I used to be an adventurer like you, then I took an arrow in the knee."
You can keep your pretentious philosophical musings and your beloved retro catchphrases. No video game quote sums up the inscrutable logic of meme culture like this one. Regularly repeated by just about every jaded guard in every town in Skyrim, this seemingly mundane line somehow captured the imagination of the entire gaming community in 2011, inspiring cartoons, short films, and millions of memes. No one really talks about it any more, but at the height of its power it was quite possibly the most viral meme ever. https://www.youtube.com/watch?v=vncIBREXCwU