The X-Files: 15 Guest Stars Who Made It Big

1. Luke Wilson (Season 5, Episode 12: "Bad Blood")

On The X-Files: Originally airing on February 22, 1998, "Bad Blood" sees Mulder and Scully dealing with an investigation gone awry. With a drugged Mulder having driven a wooden stake through the chest of a pizza delivery boy who may or may not have been a vampire and the dynamic duo facing possible legal action, Mulder and Scully share their very different sides of the story. Luke Wilson plays Hartwell, a small town sheriff who also happens to be a vampire. Most Memorable Moment: "Y'all must be the gov'ment people!" Hartwell splutters through grotesque buck teeth in Mulder's version of events. How Luke Wilson Made It Big: In the years since his appearance in fan favorite Bad Blood, Wilson has proved a surprisingly versatile actor. Perhaps best known for his role as Mitch Martin in 2003's Old School, he has played everything from romantic lead in Charlie's Angels (2000) and Legally Blonde (2001) to totally dysfunctional in The Royal Tenenbaums (2001) to downright hilarious in Anchorman (2004). With two seasons on HBO's critically acclaimed Enlightened to his name, Wilson has dabbled in quite a plethora of genres. Thankfully, without the big buck teeth. Did any other big stars first appear on screens in The X-Files? Share any missed down in the comments.
Contributor
Contributor

Fiction buff and writer. If it's on Netflix, it's probably in my queue. I've bought DVDs for the special features and usually claim that the book is better than the movie or show (and can provide examples). I've never met a TV show that I won't marathon. Follow on Twitter @lah9891 .